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Research Demonstrating Wellmune WGP® Boosts the
Immune Health of Medical Students Published in Nutrition

EAGAN, MN — April 24, 2012 — Wellmune WGP® boosted the immune systems of medical students in a new clinical study published in the peer-reviewed journal Nutrition. The research provides further evidence of this natural food, beverage and supplement ingredient’s ability to support the health of people under high stress.

Wellmune WGP is scientifically proven to activate innate immune cells that help keep the body healthy. Specifically, Wellmune primes neutrophils, the largest population of immune cells in the body and an important part of the body’s natural defenses. This award-winning functional ingredient is contained in numerous foods, beverages and supplements in more than 30 countries.

“Medical students working long hours in hospitals are placing tremendous stress on their immune systems,” said Dr. Richard Fuller, M.D. of The Dove Clinic for Integrated Medicine and principal investigator for the study. “Wellmune WGP activates innate immune cells to help protect against the harmful effects of stress.”

The citation for the paper is: Fuller R, et al., Influence of yeast-derived 1,3/1,6 glucopolysaccharide on circulating cytokines and chemokines with respect to upper respiratory tract infections. Nutrition (2012), doi: 10/1016/j.nut.2011.11.012.

Study Design & Results
The study was conducted during the peak of the 2010 cold-flu season. During the 90-day, double-blind, placebo-controlled study among 100 healthy medical students, participants taking 250 mgs of Wellmune WGP daily reported 43 fewer days of upper respiratory tract infection (URTI) symptoms than their classmates who received a placebo. The results are a strong statistical trend (p=0.06). The findings were originally presented at a British Society for Immunology conference in Liverpool, UK, in 2010.

While the authors note that larger studies are needed, results of this study demonstrated that Wellmune WGP provided real immune health benefits to the students. Specifically:

There was a reduction (18%) in the total number of days with self-reported URTI symptoms in Wellmune WGP group compared to placebo.
In total, 24 episodes of URTI were medically confirmed, 12 episodes in each group. Wellmune WGP did not induce inflammatory cytokines. No cytokine change was seen during symptomatic URTI between study groups.

“The results are consistent with eight other clinical studies regarding the immune support effects of Wellmune WGP,” said Don Cox, Ph.D., senior vice president of research and development at Biothera.

Biothera and its research collaborators have previously conducted clinical studies involving marathon runners, wildland firefighters, women and other individuals with high lifestyle stress. To learn more, go to the research page for Biothera's Healthcare Group.

About Wellmune WGP®
Wellmune WGP is a natural beta 1,3/1,6 gluco polysaccharide that is clinically proven to boost key immune cells that keep the body healthy. This unique food, beverage and supplement ingredient has regulatory approval around the world, including GRAS status in the U.S. and novel foods approval in Europe and China. It is also patented, Kosher, Halal, non-allergenic and GMO-free. In addition to receiving an IFT Innovation Award, Wellmune has received a SupplySide West Scientific Excellence Award and a Frost & Sullivan Excellence in Research Award. Wellmune WGP is a product of Biothera, a U.S. biotechnology company dedicated to improving immune health.

David Walsh
VP Communications
Biothera, the Immune Health Company


Immune Health Basics products contain Wellmune WGP®

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