You are now entering the scientifc library portion of our web site. The information contained in this section is intended to provide you with a balanced overview of information relating to the safety and efficacy of Wellmune, the active ingredient in Immune Health Basics.
Wellmune is a beta 1,3/1,6 glucan derived from a proprietary strain of baker's yeast. Its molecular structure is unique and results in biological activity that cannot be replicated by other immune health products. These articles are intended for general education purposes. This section does not constitute labeling, endorsements or advertisements and should not be interpreted as recommending how to treat any particular diseases or health-related conditions.
Biothera 's research program has generated the following studies, which include both clinical and preclinical research. Follow the links below for the official abstracts for each study.
Baker’s Yeast Beta-Glucan Supplement Reduces Upper Respiratory Symptoms and Improves Mood State in Stressed Women
Journal of the American College of Nutrition, August 2012, vol 31,
no. 4, 295-300
β-Glucan supplementation, allergy symptoms, and quality of life in self-described ragweed allergy sufferers
Food Science & Nutrition .doi: 10.1002/fsn3.11
Modification of a Beta Glucan Affects Aggregation Behavior and Biological Activity
Presented to the International Carbohydrate Symposium
Baker's Yeast Beta-Glucan Supplementation Improves Post-Exercise Mucosal Immunity and Reduces Cold/Flu Symptomatic Days in Marathon Runners
Presented to the National Strength and Conditioning Association Providence, RI.
Baker’s Yeast Beta Glucan Supplementation Reduces the Number of Cold/Flu Symptomatic Days After Completing a Marathon
Presented to the American College of Sports Medicine, San Francisco, CA.
Baker's Yeast β-glucan Supplementation Increases Monocytes and Cytokines Post-Exercise: Implications for Infection Risk?
British Journal of Nutrition, FirstView Article: pp 1-9 copyright © the authors 2012.
Influence of Yeast-Derived 1,3/1,6 Glucopolysaccharide on Circulating
Cytokines and Chemokines with Respect to Upper Respiratory Tract Infections
Nutrition 28: 665–669.
The Effects of Yeast β-Glucan Supplementation on Monocyte and Cytokine Response to Exercise.
Presented to the International Society of Exercise Immunology, University of Oxford, UK.
Activation of the Innate Immune Receptor Dectin-1 upon Formation of a ‘Phagocytic Synapse’
Nature 472, 471–475.
Baker’s Yeast Beta-Glucan Supplement Reduces Allergy Symptoms and Improves Quality of Life in Ragweed Sufferers
Presented to Experimental Biology 2011, Washington, D.C.
A randomised controlled trial to assess the ability of yeast-derived 1,3/1,6 glucopolysaccharide to reduce upper respiratory tract infection symptoms.
Presentation: The British Society of Immunology. Publication pending
Presentation: Experimental Biology, 2010. Publication pending.
Beta 1,3/1,6 Glucan Decreases Upper Respiratory Tract Infection Symptoms and Improves Psychological Well-being in Moderate to Highly-Stressed Subjects.
Agro Food Industry Hi-Tech (2010) 21:21-24.
Effect of Beta 1, 3/1, 6 Glucan on Upper Respiratory Tract Infection Symptoms and Mood State in Marathon Athletes.
Journal of Sports Science and Medicine (2009). 8:509-515.
Randomized Phase II Clinical Trials of Wellmune WGP® for Immune Support During Cold and Flu Season.
The Journal of Applied Research (2009) 9:20-42.
Presentation: American College of Sports Medicine. Publication pending.